Mono may refer to:
Biology
Infectious mononucleosis, "the kissing disease" Monocyte, a type of leukocyte (white blood cell) Monodactylidae, members of which are referred to as monos
Technology and computing
Mono (audio), single-channel sound reproduction
Mono (software), a software framework
Music
Performers
Mono (Japanese band), an instrumental band
Mono (UK band), an electronic band
MONO, Vietnamese male singer, Son Tung M-TP's younger brother
Miky Mono, former member of Mono Inc., a German gothic rock band
Richard Targett and the Monos, a side-project to The Trudy
Albums
Mono (Alpha Wolf album) or the title song, 2017
Mono (Fury in the Slaughterhouse album), 1993
Mono (K.Flay album), 2023
Mono (The Icarus Line album), 2001
Mono (Lena Katina album) or the title song, 2019
Mono (The Mavericks album), 2015
Mono (mixtape), by RM, 2018
Mono, by Paul Westerberg, packaged with Stereo, 2002
Songs
"Mono" (song), by Courtney Love, 2004
"Mono", by Fightstar from They Liked You Better When You Were Dead, 2005
"Mono", by Monrose from Ladylike, 2010
"Mono", by Whitechapel from Our Endless War, 2014
Places
United States
Mono or Mono Mills, California, a ghost town
Mono County, California
Mono Village, Mono County, California, a former settlement
Mono Lake, California
Mono Pass, Yosemite National park, California
Elsewhere
Mono Department, Benin
Mono, Ontario, Canada, a town
Monó, Romania, a village
Mono Island, Solomon Islands
Mono River, Togo
Ethnicities and languages
Mono people, an ethnic group of California
Mono language (California) Mono people (Congo), an ethnic group the Democratic Republic of the Congo Mono language (Congo) Mono language (Cameroon) Mono language (Solomon Islands), a dialect of Mono-Alu
Other uses
Mono-, a numerical prefix representing anything single
BAC Mono, a British sports car which began production in 2011
Mono, a character in the video game Little Nightmares II
Mono, a character in the video game Shadow of the Colossus
Mono (film), a 2016 American film featuring Sam Lerner
Monomorphism, in abstract mathematics
Order of Mono, a Togolese order of chivalry
José María Gatica (1925–1963), Argentine boxer nicknamed "El Mono"