From the epidemiological standpoint it is interesting to know the dimensions and location of the cages in which the animals were kept.
Aside from the 2 rats which were confined in ordinary traps that stood on a table 80 centimetres high, the rest of the animals were kept in regular metal animal cages. The dimensions of the cages are: Fifty centimetres long, 36 centimetres broad, and 30 centimetres high. The cage stands on four legs each 10 centimetres long; the centre of the bottom of the cage holds a drain opening 8 centimetres above the floor.
The majority of the cages in room II were located on the floor; some on the second shelf of a wooden rack. This last-mentioned arrangement, judging from the construction of the wooden frame, allowed a continuous passageway for the fleas to the second shelf of the racks. On the other hand, the deaths among the guinea-pigs in room V were restricted to the cages standing on the floor, the majority of cages in that room being placed on tables 80 centimetres high.
Only a theoretical explanation can be given of the short duration and sudden cessation of the outbreak. One can assume with great probability that the first partial disinfection drove the fleas away from the primary source of infection, and that they traveled as far as possible. They finally settled in those guinea-pig cages which had not been molested by the first disinfection. Having no new supply of plague blood (all of the plague-infected guinea-pigs having been removed, most of them before death), the fleas soon cleared themselves of plague bacilli. The peculiar feature of the outbreak, namely, the failure to find fleas on the animals in rooms II and V, finds its explanation in the observation of the Indian Commission who found that the fleas "died or disappeared very rapidly."
The following conclusions can be drawn from these observations:
1. The common rat flea (_Lœmopsylla cheopis_) prefers the rat to the guinea-pig.
2. In the absence of rats it will attack guinea-pigs rather than rabbits.
3. The fleas which have sucked blood from rats or guinea-pigs afflicted with plague septicæmia were found to harbor virulent plague bacilli inside of their bodies.
4. The transmission of plague infection by direct or indirect contact being excluded in our case, the fact that fleas of the same species and harboring plague bacilli were found on the rat and on the guinea-pigs, the presence of flea bites on the rats and on the guinea-pigs with positive findings of skin lesions on that part of the body where the fleas and flea bites were located, together with the anatomical picture of the findings in the guinea-pigs, lead to but one explanation; namely, that the plague infection was transmitted by fleas.