Retreat is a historic home located at Port Tobacco, Charles County, Maryland, United States. It is a one-story, clapboard-sheathed, frame house with a double chimney. The principal part of the house was built about 1770. Also located on the property is a frame, pyramid-roofed meathouse, dating from the early 19th century, and moved here from another historic property in the county known as "Brentland" in 1953. The home, approached by a private gravel road, is surrounded by cultivated fields, meadows, and woodland, preserving its original agricultural and rural setting. The house is one of the earliest known examples of the side-passage, two-room dwelling in Charles County. It is associated with Daniel of St. Thomas Jenifer and Daniel Jenifer.
Retreat was listed on the National Register of Historic Places in 1988.