Shrewsbury House was built in the reign of Henry VIII. by George, Earl of Shrewsbury, who was succeeded in 1538 by his son Francis. The son of Francis, George, sixth Earl of Shrewsbury, who succeeded in his turn, was a very wealthy and powerful nobleman. He was high in Queen Elizabeth's favour, and it was to his care that the captive Mary, Queen of Scots, was entrusted. Though Elizabeth considered he treated the royal prisoner with too much consideration, she afterwards forgave him, and appointed him to see the execution of the death-warrant. He married for his second wife a lady who had already had three husbands, each more wealthy than the last. By the second of these, Sir William Cavendish, she had a large family. Her husband left his house at Chelsea wholly to her. She outlived him seventeen years, and with her immense wealth built the three magnificent mansions of Chatsworth, Oldcotes, and Hardwick, and all these she left to her son William Cavendish, afterwards created Baron Cavendish and Earl of Devonshire. A son of a younger brother was created Marquis of Newcastle, and his daughter and coheiress was Lady Jane, who brought her husband, Charles Cheyne, such a large dower that he was enabled to buy the Manor of Chelsea.
After the death of the Earl of Devonshire, Shrewsbury House became the residence of his widow until her death in 1643. It then was held by the Alstons, from whom it took its secondary name, and was finally in the possession of the Tates, and was the seat of a celebrated wall-paper manufactory. "The manufacture of porcelain acquired great celebrity. It was established near the water-side.... Upon the same premises was afterwards established a manufactory of stained paper." This seems to point to Shrewsbury House as the original home of the celebrated Chelsea china. But, on the other hand, all later writers point authoritatively to Lawrence Street, at the corner of Justice Walk, as the seat of the china manufacture. There seems to be some confusion as to the exact site of the original works, for in "Nollekens and his Times" it is indicated as being at Cremorne House, further westward. One Martin Lister mentions a china manufactory in Chelsea as early as 1698, but the renowned manufactory seems to have been started about fifty years later. The great Dr. Johnson was fired with ambition to try his hand at this delicate art, and he went again and again to the place to master the secret; but he failed, and one can hardly imagine anyone less likely to have succeeded. The china service in the possession of Lord Holland, known as Johnson's service, was not made by him, but presented to him by the proprietors as a testimony to his painstaking effort. The first proprietor was a Mr. Nicholas Sprimont, and a jug in the British Museum, bearing date "1745 Chelsea," is supposed to be one of the earliest productions.