As the disorder advances to a more inveterate malignity, these pustules burst, the scab or eschar exfoliates, and each becomes a virulent, ill-conditioned _ulcer_. In many instances the progress is extended with incredible rapidity; and the larger vessels, with their inferior ramifications, are soon universally affected; holding forth a very unpromising prediction of early extrication. A tolerable opinion may be formed of the mildness or threatened severity of the disease by the nature of the attack: if appearances are partial, (that is, attached to any particular spot,) without a speedy extension to different parts of the body, or its extremities, the case may be considered in its then _infantine state_ favourable; and the proper means should not be delayed to counteract its farther contamination of the blood and juices: on the contrary, should a daily increase of the eruption be observed, spreading itself in various directions along the plate-vein, and down the inside of the fore-arm, under the belly, proceeding on both sides the sheath, and down the inside of each thigh, a cure may be considered very _distant_ and _uncertain_; involving a doubt for prudent deliberation, whether the alternative of DEATH may not be preferable to the _chance_ of _cure_, at an expence (if effected) very, very far exceeding the value of THE HORSE.
Experience, and attentive observation, tend to justify an opinion, that when the FARCY makes its first appearance, in the way described, it is then of the species received by _infection_, and that it has lain dormant some time in the circulation. When it makes its attack upon one particular part, in a previous _tumefaction_, and subsequent _suppuration_, (extending no farther than the quarter in which it originates,) it may then be considered a degree of the same disorder, retaining within itself much _less virulence_ than the former, and to have been produced by the morbid state of the blood, and predominant tendency to disease; holding forth a well-founded prospect of CURE, if the case happens to fall into the hands of a judicious and scientific practitioner, who well knows the peculiar _property_ of _medicine_, upon which alone the success depends.