Izaak Maurits (Piet) Kolthoff (February 11, 1894 – March 4, 1993) was an analytical chemist and chemistry educator. He is widely considered the father of analytical chemistry for his large volume of published research in diverse fields of analysis, his work to modernize and promote the field, and for advising a large number of students who went on to influential careers of their own.

Kolthoff's best-known research contribution was the development of the "cold process" for producing synthetic rubber, which he undertook under the U.S. synthetic rubber program during World War II. He was also active in social causes, including promoting world peace and opposing nuclear weapons testing.

Izaak Kolthoff

Kolthoff received a PhD in chemistry from the University of Utrecht in his native Netherlands. In 1927, he immigrated to the United States, joining the faculty at the University of Minnesota, where he worked for more than 60 years.

Izaak Kolthoff

Early life and education

Kolthoff was born in Almelo, Netherlands, on February 11, 1894, the son of Moses and Rosetta (Wysenbeek) Kolthoff. He was the youngest of three children. At an early age, Kolthoff received the nickname "Piet" for unknown reasons; he continued to be called by this nickname throughout his life.

Izaak Kolthoff

Kolthoff's introduction to chemistry in high school inspired a keen interest in the subject. He graduated from high school in 1911 and enrolled at the University of Utrecht in Utrecht, Netherlands. Kolthoff wanted to study chemistry, but at that time students in the physical sciences were required to have studied either Latin or Greek languages; Kolthoff, who was already fluent in Dutch, German French, and English, choose to study pharmacy in order to avoid this requirement.

The pharmacy program at Utrecht provided a strong foundation in analytical chemistry. There Kolthoff met Nicholas Schoorl, a professor of pharmacy who became his academic adviser. Schoorl's instruction in analytical chemistry provided an emphasis on fundamental chemical principles, which was unusual at the time. He introduced Kolthoff to research in the areas of electro-analytical chemistry and co-precipitation. He also advised Kolthoff to approach analytical chemistry from a scientific perspective as opposed to an empirical one. Kolthoff would adopt and later promote Schoorl's adage towards research, "Theory guides, experiment decides."

Kolthoff published his first paper in 1915 on pH, a concept that had been introduced by S. P. L. Sørensen in 1909. Also in 1915, Kolthoff obtained an "apotheker" degree in pharmacy. He continued his education at Utrecht with advanced courses in physical and colloid chemistry. When the classical language requirement for physical sciences was lifted in 1918, Kolthoff received a PhD in chemistry from the University of Utrecht. By the time he received his doctoral degree, Kolthoff had already published 32 papers in several fields.

Career

Kolthoff remained at the University of Utrecht as a lecturer in electrochemistry and a researcher until 1927. During this time he authored or coauthored 270 papers and three books and promoted the concept of pH, which was not well understood at the time. He also conducted a lecture tour of the United States and Canada in 1924. These activities earned him an international reputation.

In 1927 he was offered a one-year appointment at the University of Minnesota. He accepted the position and continued his research and writing, producing English translations and expansions of much of his previous work. The position became permanent, and soon he became professor and chief of the analytical division of the University's school of chemistry.

During World War II, Kolthoff worked on a U.S. government-backed research program to develop a synthetic method for producing rubber, and he served as chairman of the Committee on Analytical Research Methods and supervisor of three research projects related to the project. His research in emulsion polymerization and development of a low-temperature "cold process" for producing synthetic rubber were among his most well-known research contributions.

Kolthoff retired in 1962, at which time he had authored 809 research papers. After his retirement, he continued working and published an additional 136 papers, bringing his career total to 945.