Radcliffe is a surname. Notable people with the name include:
Alex Radcliffe (1905–1983), US baseball player
Ann Radcliffe (1764–1823), English novelist
Aubrey Radcliffe (1933–2009), US academic
Bill Radcliffe (1917–1984), Manx teacher and Manx-Gaelic language advocate
Charles Radcliffe (born 1941), English magazine editor
Cyril Radcliffe, 1st Viscount Radcliffe (1899–1977), British lawyer
Daniel Radcliffe (born 1989), English actor
Egremont Radcliffe (died 1578), English rebel
Eric Radcliffe, British recording engineer and music producer
George Radcliffe (politician) (1593–1657), English politician
George L. P. Radcliffe (1877–1974), US Senator from Maryland
Jacob Radcliff (1764–1844), US politician
John Radcliffe, disambiguation
Mark Radcliffe, disambiguation
Mary Radcliffe, disambiguation
Melva Radcliffe (1901–2012), supercentenarian from in New Jersey
Mike Radcliffe (born 1944), Canadian politician
Paula Radcliffe (born 1973), English athlete
Percy Radcliffe (1916–1991), Manx politician, member of the Legislative Council of the Isle of Man Richard Radcliffe (died 1660), English politician who sat in the House of Commons in 1656 Rip Radcliff (1906–1962), American baseball player Rosemary Radcliffe (born 1949), Canadian actress Ted Radcliffe (1902–2005), US baseball player Timothy Radcliffe (born 1945), former Master of the Order of Preachers (Dominicans) 1992–2001