The 2018 Lafayette Leopards football team represented Lafayette College in the 2018 NCAA Division I FCS football season. The Leopards were led by second-year head coach John Garrett and played their home games at Fisher Stadium. They were a member of the Patriot League. They finished the season 3–8, 2–4 in Patriot League play to finish in a three-way tie for fourth place.
Preseason
Preseason coaches poll
The Patriot League released their preseason coaches poll on July 26, 2018, with the Leopards predicted to finish in a tie for fifth place.
Preseason All-Patriot League team
The Leopards placed four players on the preseason all-Patriot League team.