Virginia Zakian is the Harry C. Wiess Professor in the Life Sciences in the Department of Molecular Biology at Princeton University. She is the director of the Zakian Lab, which has done important research in topics such as telomere-binding protein, telomere recombination, and telomere position effects, at Princeton University. She is a fellow at the American Academy of Microbiology and the American Association for the Advancement of Science., and is an elected member of the National Academy of Sciences (2018). Zakian served as the chair of "Princeton's Task force on the Status of Women Faculty in the Natural Sciences and Engineering at Princeton" from 2001-2003, in 2003 Zakian became Princeton University's representative to Nine Universities, Gender Equity Analysis She was elected as a member of the American Academy of Arts and Sciences in 2019.
Education and career
Zakian completed her A.B. in Biology at Cornell University, graduating cum laude and with distinction in all subjects, in 1970. Zakian went on to pursue graduate work in Biology at Yale University, while she was working on her Ph.D. (1970–1973) she received a NSF predoctoral fellowship. In 1975, Zakian completed her Ph.D. in Biology, her thesis was supervised by Joseph G. Gall and concerned "DNA replication in Drosophila." Zakian served as a postdoctoral fellow at Princeton University from 1975–1976, during this time she conducted research on "animal virus replication" with Dr. AJ Levine. Later in 1976, Zakian continued her postdoctoral research at the University of Washington where she worked on research concerning "yeast DNA Replication" with Dr. WL Fangman.
In 1978, Zakian joined the Fred Hutchinson Cancer Research Center as an assistant member, Zakian was promoted to the position of an "associate member" in 1984 and to the position of"full member" in 1987. During her time at the Fred Hutchinson Cancer Research Center, Zakian published or co-published around sixty articles in peer-reviewed journals like Nature (journal), Cell (journal), Proceedings of the National Academy of Sciences of the United States of America and the Journal of Molecular Biology. Additionally, during her stay at Fred Hutchinson, Zakian served as either an editor, associate editor or member of the editorial board of journals such as: Plasmid (1986–90), Chromosoma (1990–), J. Exptl. Zoology (1991–96), Trends in Cell Biology (1991–97), Molecular and Cellular Biology (1992–98), Genes to Cells (1994–98).
In 1995, Zakian was appointed as a professor in the Department of Molecular Biology at Princeton University. Zakian was awarded the Harry C. Wiess Professor in the Life Sciences in the Department of Molecular Biology in the year 2000, a position that she holds to this day. Zakian served as the chair of "Princeton's Task force on the Status of Women Faculty in the Natural Sciences and Engineering at Princeton." from 2001-2003, in 2003 Zakian became Princeton University's representative to Nine Universities, Gender Equity Analysis
Research Area
Zakian has published 150 papers in peer-reviewed journals throughout her career. Most of Zakian's research concerns telomeres, which are "the region[s] of repetitive nucleotide sequences at each end of a chromatid, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes." Zakian's lab " uses a combination of genetic, biochemical, and cell biological approaches to identify proteins that affect telomeres and to determine their mechanism of action." One of the lab's "major goal[s] is to understand how telomeres, the physical ends of chromosomes, contribute to chromosome stability."