The 2022 UniCredit Czech Open was a professional tennis tournament played on clay courts. It was the 29th edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Prostějov, Czech Republic between 30 May and 4 June 2022.
Singles main-draw entrants
Seeds
1 Rankings are as of 23 May 2022.
Other entrants
The following players received wildcards into the singles main draw: Martin Krumich Hamad Međedović Lukáš Pokorný
The following player received entry into the singles main draw as a special exempt: Lukáš Klein
The following player received entry into the singles main draw as an alternate: Vitaliy Sachko
The following players received entry from the qualifying draw: Térence Atmane Francisco Comesaña Martín Cuevas Alexander Erler Fábián Marozsán Lucas Miedler
The following players received entry as lucky losers: Benjamin Hassan Calvin Hemery Louis Wessels
Champions
Singles
Vít Kopřiva def. Dalibor Svrčina 6–2, 6–2.
Doubles
Yuki Bhambri / Saketh Myneni def. Roman Jebavý / Andrej Martin 6–3, 7–5.