Schizozygia is a monotypic genus of plant in the family Apocynaceae found in tropical Africa and the Comoros. , Plants of the World Online recognises the single species Schizozygia coffaeoides.
Schizozygia coffaeoides grows as a shrub or small tree up to tall. Its fragrant flowers feature a creamy-yellow corolla. Fruit is yellow to orange with paired ellipsoid follicles, each up to long. Its habitat is forests from sea level to altitude. Local medicinal uses include as a treatment for eye inflammation, sores and ringworm-infected skin. Schizozygia coffaeoides is native to the Democratic Republic of the Congo, Somalia, Kenya, Tanzania, Angola, Malawi and the Comoros.